CPT / HCPCS code · 2026 CMS data · Verified 2026-08-31
CPT 96401 RVU and Medicare Payment (2026)
Chemo anti-neopl sq/im — 0.21 work RVU, about $71.81 non-facility Medicare payment at the 2026 conversion factor.
- Work RVU
- 0.21
- PE RVU (non-facility)
- 1.9
- PE RVU (facility)
- 1.9
- MP RVU
- 0.04
- Office payment
- $71.81
- Facility payment
- $71.81
How the payment is calculated
Total RVU is work plus practice expense plus malpractice, each adjusted by its GPCI factor, then multiplied by the conversion factor. For 96401 in a non-facility setting with national GPCI: (0.21 + 1.9 + 0.04) × $33.4009 ≈ $71.81. The same code in a facility setting pays about $71.81 because facility PE RVU (1.9) replaces office PE RVU.
What changes by locality
GPCI moves 96401 non-facility payment from $62.22 to $100.01 across CMS localities — from Arkansas to San Jose-sunnyvale-santa Clara (san Benito Cnty). Check your exact locality in the GPCI calculator rather than using a state average.
Related codes
Checking a different code or locality? Open the full RVU calculator to run any of the 7,790 CPT/HCPCS codes with your own GPCI factors.
Frequently asked questions
What is the 2026 work RVU for CPT 96401?
0.21. Work RVU measures physician time, skill, and intensity — it does not change by setting or locality. Total payment adds practice expense and malpractice RVUs plus the conversion factor.
How much does Medicare pay for CPT 96401 in 2026?
About $71.81 non-facility ($71.81 facility) at national GPCI with the 2026 $33.4009 conversion factor. Your locality GPCI moves the number — see the range above.
Does the work RVU change between office and facility?
No. Work RVU (0.21) and malpractice RVU stay fixed; only practice expense changes (1.9 office vs 1.9 facility). That is the entire office-vs-facility payment gap.