CPT / HCPCS code · 2026 CMS data · Verified 2026-08-31

CPT 48100 RVU and Medicare Payment (2026)

Biopsy of pancreas open — 14.1 work RVU, about $844.04 non-facility Medicare payment at the 2026 conversion factor.

Work RVU
14.1
PE RVU (non-facility)
7.61
PE RVU (facility)
7.61
MP RVU
3.56
Office payment
$844.04
Facility payment
$844.04

How the payment is calculated

Total RVU is work plus practice expense plus malpractice, each adjusted by its GPCI factor, then multiplied by the conversion factor. For 48100 in a non-facility setting with national GPCI: (14.1 + 7.61 + 3.56) × $33.4009 ≈ $844.04. The same code in a facility setting pays about $844.04 because facility PE RVU (7.61) replaces office PE RVU.

What changes by locality

GPCI moves 48100 non-facility payment from $750.51 to $1,042.65 across CMS localities — from Nebraska to Alaska. Check your exact locality in the GPCI calculator rather than using a state average.

Related codes

Checking a different code or locality? Open the full RVU calculator to run any of the 7,790 CPT/HCPCS codes with your own GPCI factors.

Frequently asked questions

What is the 2026 work RVU for CPT 48100?

14.1. Work RVU measures physician time, skill, and intensity — it does not change by setting or locality. Total payment adds practice expense and malpractice RVUs plus the conversion factor.

How much does Medicare pay for CPT 48100 in 2026?

About $844.04 non-facility ($844.04 facility) at national GPCI with the 2026 $33.4009 conversion factor. Your locality GPCI moves the number — see the range above.

Does the work RVU change between office and facility?

No. Work RVU (14.1) and malpractice RVU stay fixed; only practice expense changes (7.61 office vs 7.61 facility). That is the entire office-vs-facility payment gap.