CPT / HCPCS code · 2026 CMS data · Verified 2026-08-31
CPT 45380 RVU and Medicare Payment (2026)
Colonoscopy and biopsy — 3.47 work RVU, about $479.97 non-facility Medicare payment at the 2026 conversion factor.
- Work RVU
- 3.47
- PE RVU (non-facility)
- 10.48
- PE RVU (facility)
- 1.43
- MP RVU
- 0.42
- Office payment
- $479.97
- Facility payment
- $177.69
How the payment is calculated
Total RVU is work plus practice expense plus malpractice, each adjusted by its GPCI factor, then multiplied by the conversion factor. For 45380 in a non-facility setting with national GPCI: (3.47 + 10.48 + 0.42) × $33.4009 ≈ $479.97. The same code in a facility setting pays about $177.69 because facility PE RVU (1.43) replaces office PE RVU.
What changes by locality
GPCI moves 45380 non-facility payment from $423.81 to $640.93 across CMS localities — from Arkansas to San Jose-sunnyvale-santa Clara (san Benito Cnty). Check your exact locality in the GPCI calculator rather than using a state average.
Related codes
Going deeper: in-depth CPT 45380 RVU guide.
Checking a different code or locality? Open the full RVU calculator to run any of the 7,790 CPT/HCPCS codes with your own GPCI factors.
Frequently asked questions
What is the 2026 work RVU for CPT 45380?
3.47. Work RVU measures physician time, skill, and intensity — it does not change by setting or locality. Total payment adds practice expense and malpractice RVUs plus the conversion factor.
How much does Medicare pay for CPT 45380 in 2026?
About $479.97 non-facility ($177.69 facility) at national GPCI with the 2026 $33.4009 conversion factor. Your locality GPCI moves the number — see the range above.
Does the work RVU change between office and facility?
No. Work RVU (3.47) and malpractice RVU stay fixed; only practice expense changes (10.48 office vs 1.43 facility). That is the entire office-vs-facility payment gap.